I'm a chronic pain sufferer and I am prescribed strong pain relief medicine. When I run out early I have taken to using Kratom. In my experience taking enough to stop withdrawal or even have good effects means your tolerance doesn't go down at all. Which makes sense given the way the active chemicals work. When I've used it for over a week continuously I've found it to actually raise my tolerance to "real" pain relief even, to the the degree that I need way more to get my normal relief. It's